Cognition - Food for Thought
The brain has a colossal energy requirement for its size, 22% of the body’s oxygen consumption is used by an organ that is roughly 2% of an adult’s body weight [1]. The brain requires this amount of oxygen in order to process glucose into energy [1]. Almost 97% of a healthy adult’s brain fuel requirement is satisfied by glucose, the remainder comes from ketones [1, 2]. However, as we age, ketones can provide over 60% of the brain’s fuel requirement [3]. Glucose uptake in the brain decreases as we age, human studies have shown that glucose uptake may decrease 10-15% in the elderly compared to non-elderly subjects [4-7]. Further evidence suggests subjects with Alzheimer's disease have 20-25% decrease in glucose uptake [4-7]. It has been proposed that glucose use and/or uptake by the brain can diminish long before clinical cognitive decline is noted, especially if one has genetic Alzheimer’s predisposition [7]. Learning and memory may also be affected by glucose deficit conditions [8-10]
Featuring: Captex® 8000 (high C8 content MCT)
ABITEC's Captex medium-chain triglycerides come in a variety of grades, each with unique characteristics for different formulations. Our Captex 8000 MCT contains 98% C8 acyl groups.
Medium-chain triglycerides (MCT) are fats typically containing 8-12 carbons. Each MCT can vary in C8-C12 content. Captex 8000, with its high content of C8 acyl groups, has fewer carbons than fats (triglycerides) with longer acyl groups. This is noteworthy because studies have shown that ingestion of MCTs with high C8 significantly increases the ketone production compared to longer-carbon MCTs [11,12]. A recent study from Cunnane et al, showed C8 fatty acids derived from such MCTs increases blood ketones 3 times more than C10 over an 8-hour period [13].
ABITEC's Captex 8000 can be taken alone or incorporated into a wide range of different formulations such as:
- Ready-to-drink (RTD) Beverages
- Bars
- Gelpaks
- Energy Shots
- Coffee Creamers
|
Product Name |
Chemical Name | Caprylic (C8) fatty acid content (%) | Capric (C10) fatty acid content (%) | CAS Number |
| Captex 8000 | Glyceryl Tricaprylate | 98 | <1 | 538-23-8 |
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