LNP Therapeutics

Developing complex lipid chemistries is crucial for developing next-generation therapies. ABITEC’s services can help you design and produce the custom lipid chemistries your formulation needs, providing scalable, ultra-pure lipids from state-of-the-art facilities to accelerate your path to market.

Solve your most complex lipid chemistry challenges

Navigating complex lipid chemistry challenges to develop the next generation of lipid nanoparticles requires an expansive range of organic chemistry and scale-up manufacturing expertise.

Whether you're in industry or academia, partnering with an experienced LNP developer ensures both technical excellence and exceptional customer service for smooth collaboration and successful project outcomes.

CDMOs

Ensuring a consistent supply of ultra-pure lipids that meet your customer’s unique formulation and scale up requirements is critical. Without tailored solutions and unwavering quality, you risk delays, inefficiencies, and unmet client expectations.

How we help

  • Expand your service offering: Become a one-stop shop by incorporating our reliable, complex lipid-based drug delivery solutions, attracting new customers and projects.
  • Leverage extensive expertise: Skip the learning curve by tapping into our 100+ years of combined experience in complex lipid chemistry. Work directly with our experts to design, develop and deliver cutting-edge solutions without the need for costly in-house expertise.
  • Experience seamless scale-up: Transition smoothly from research to clinical quantities with our flexible and scalable production capabilities.
  • Ensure quality: ABITEC is on-boarding its cGMP-certified facilities in 2025 to ensure stringent quality control to meet the highest industry standards, providing peace of mind for regulatory compliance.

Academia and research institutes

Securing funding, sourcing the right lipid chemistry solutions and connecting with the right experts are all crucial for research success. Without these, you risk stalled progress, lack of scientific rigor and the potential of missed opportunities for additional research funding.   

How we help

  • Engage in collaborative research partnerships: Work side-by-side with our team of experienced lipid chemists to design, optimize and deliver custom lipid solutions that are tailored to your specific research goals.
  • Strengthen your grant proposals: Increase your chances of securing funding for cutting-edge lipid-based research projects with our expert guidance and support.
  • Achieve publication-worthy results: Rely on our ultra-high purity lipids to deliver reliable and reproducible outcomes, maximizing your chances of publication in high-impact journals.
  • Leverage advanced technologies and expertise: Access state-of-the-art lipid chemistry technologies and our extensive knowledge base to push the boundaries of your research, driving innovations in next-generation therapies.

Biopharma and pharma

Overcoming drug delivery challenges is essential for the development of next-gen therapeutics. Without access to custom lipid chemistry solutions, as well as reliable and scalable production capabilities, you risk development delays and increased costs. 

How we help

  • Access tailored lipid chemistry solutions: Advance your therapeutics using our next-gen lipid chemistry expertise.
  • Enhanced drug efficacy: Improve the solubility, permeability, and bioavailability of your drug candidates.
  • Accelerate time to market: Seamlessly scale from research to clinic with our reliable services.
  • Ensure quality and ease regulatory compliance: Rely on our internal Regulatory team to support your regulatory documentation requirements and streamline the approval process.

 

Frequently asked questions

Manufacturing

Where are ABITEC’s lipids for LNP therapeutics manufactured? 
ABITEC manufactures its Research Use Only (RUO) and cGMP grade lipids for LNP therapeutics in multiple facilities throughout Europe. All our cGMP lipids are manufactured in cGMP-certified, API-grade facilities.  
 
What manufacturing volumes can ABITEC accommodate for RUO lipids?
ABITEC can manufacture RUO lipids in quantities ranging from milligrams to several hundred grams. We deliver the lipids customers need at the desired scale.

What manufacturing volumes can ABITEC accommodate for cGMP lipids?
ABITEC’s dedicated cGMP-certified facilities can manufacture cGMP lipids in quantities ranging from low grams to multiple kilograms. We deliver the lipids customers need at the desired scale.

Can ABITEC support clinical scale manufacturing?
Yes. ABITEC can scale production seamlessly to deliver kilogram quantities of cGMP lipids for clinical trials. We also support with process and analytical method development, process validation, and can provide regulatory support (including provision of CMC files).

Can ABITEC support tech transfer of manufacturing protocols?
Yes. ABITEC has an experienced team that can support tech transfer of lipid manufacturing protocols to a CDMO of choice. In all tech transfer operations, we operate transparently and in a collaborative manner to ensure the transfer is as smooth as possible.

To find out more about how we can support clinical scale projects or specific technology transfer requirements, contact our team today. 

Supply

How does ABITEC ensure a reliable supply of lipids for customers?
Unlike many lipid providers, ABITEC can offer a reliable supply of high-purity custom lipids thanks to its redundant manufacturing facilities, global warehousing and distribution network, and operations backed by global specialty ingredients group ABF Ingredients (part of the ABF Group). We also have extensive experience in managing complex projects to tight timelines.

Have an urgent project you’d like to discuss? Contact our team today to find out how we can help.

Purity and performance

How does ABITEC determine the purity of manufactured RUO or cGMP grade lipids?
ABITEC uses comprehensive analysis  to determine the structure and purity profiles of the lipids that it manufactures. Thanks to our team, expertise, and facilities, we are able to deliver lipids of 99%+ purity, consistently.

Does ABITEC evaluate the performance of its customized lipids in LNP formulations?
Yes. ABITEC has a trusted network of industrial and academic collaborators that assists in assessing the characteristics and performance of ABITEC’s ultra-pure custom lipids in LNP formulations.  

Chemistries

Does ABITEC have a library of novel ionizable lipids that could be tested in formulations and licensed?
ABITEC currently holds an extensive library of ionizable lipids that can be tested and licensed, and continues to add to this library every year. We also have the team, tools, experience, and expertise to design and synthesize ultra-high purity custom ionizable lipids tailored to customers’ specific needs. 

For specific questions about your ionizable lipid requirements, contact our team today.

What types of chemistries can ABITEC accommodate for custom lipid synthesis?
ABITEC can produce a vast range of custom lipid chemistries, including:

  • Ionizable lipids
  • Lipids with biodegradable moieties, such as disulfide linkages or carboxyl groups
  • Lipids with click chemistry or conjugation functional groups
  • Lipids containing stable isotope labels, such as deuterate
  • And much, much more.

To discover the full range of chemistries we can accommodate, contact one of our lipid chemistry experts today.    

Why choose ABITEC for polar lipids?

  • Based at our Larodan facility, in the world renowned Karolinska Institute in Stockholm, our specialist team includes some of the leading experts in this field.
  • With more than 60 years of lipid manufacturing experience, ABITEC sets the standard for top quality, high-purity polar lipids. 
  • Backed by global specialty ingredients group, ABF Ingredients (part of the ABF Group),  ABITEC benefits from the stability of a recognized industry leader whilst retaining the agility, enterprise and innovation of an SME.
  • We are focused on customer satisfaction with a proven and trusted commitment to excellence
  • With our capability to customize any lipid, we will ensure that every requirement is met with precision and care to adhere to the highest industry standards.
Get in touch with our team