ABISORB-DC™ Co-processed Excipient System

ABISORB-DC™ is a co-processed excipient system. It allows manufacturers to make direct compression tablets with liquid lipids and other lipophilic excipients without the need for specialized equipment or processes.

ABISORB-DC™ combines the enhanced bioavailability of lipid-based drug delivery with the easy manufacturing and high throughput of direct compression tableting using standard equipment.

ABISORB-DC™ is designed to balance tablet compaction with liquid lipid absorption. It facilitates the complete absorption of both single-lipid and SEDDS systems into the excipient system whilst still being suitable for processing on industry standard tableting equipment such as granulators, mixers and rotary tablet presses. What's more, SEDDS tablets can be compacted at industry press speeds.

Properties

ABISORB-DC™ is the ideal lipid-carrying direct compression tableting system.

  • Manufactured from compendial excipients
  • Free-flowing powder
  • High lipid absorbing capacity (20-25% w/w)
  • Large surface area
  • Inert
  • Easy to handle
  • Easy to blend
  • Highly compactable
  • Non-sticking to tablet punches, dies or other tableting surfaces

Physical Characteristics

Bulk Density 0.28 g/mL
Tapped Density 0.40 g/mL
Skeletal Density 1.78 g/mL
Surface Area 76.9 m2/g
Carney Flow 0.39 g/sec

Manufacturing with ABISORB-DC™

Producing tablets with ABISORB-DC™ involves a simple four-step process with standard equipment such as reactors, hi-shear granulators, mixers and rotary tablet presses:

Manufacture of 10mg loratadine SEDDS tablets with ABISORB-DC

10mg loratadine SEDDS were successfully manufactured with ABISORB-DC. You can request a copy of our white paper below.

ABISORB is a registered trademark of ABITEC Corporation. All information and statements given on this website are believed to be accurate at the time of publication .However, neither ABITEC Corporation nor any of their affiliates make any representations or warranty with respect thereto, including, but not limited to, any results obtained in the processing of the products by customers or any third party. All information and statements are intended for persons having the required skill and know-how and do not relieve the customer or user from verifying the suitability of information and statements given for a specific purpose prior to use of the products. It is entirely the obligation of the customer or user to comply with applicable laws and regulations, and also with all patent or other intellectual property rights of third parties. ABITEC CORPORATION EXPRESSELY DISCLAIMS ANY REPRESENTATIONS OR WARRANTIES OF ANY KIND, WHETHER EXPRESSED OR IMPLIED, AS TO THE ACCURACY, CURRENCY, COMPLETENESS AND/OR THE MERCHANTABILITY OR FITNESS OF A PARTICULAR PURPOSE OF ANY INFORMATION CONTAINED IN THIS BROCHURE AND/OR PRODUCT DESCRIBED OR PROMOTED IN THIS BROCHURE, INCLUDING WARRATNTIES WITH RESPECT TO INFRINGEMENT OF ANY PATENT, COPYRIGHT, OR OTHER RIGHTS OF A THIRD PARTY. We reserve the right to change product specification and it specified properties of the products without prior notice.